Long-term couple John and Ella Robina are experiencing the struggles of growing older. With John having Alzheimer's and Ella undergoing cancer treatment, they decide to abandon their disease-stricken lifestyles and embark on a journey from Boston to Key West in an attempt to fully live what's left of their lives. Their trusty RV, which they've dubbed "The Leisure Seeker", will be their mode of transportation as they enjoy what may be their last adventure...

When his best friend suddenly dies, Charlie drives off into the country where he comes across a lonely hotel with a landlocked lighthouse. Here he meets many fascinating characters, including an attractive vagrant who will change his life forever.